San Jose Eye Institute

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DURYSTA implant is now available

DURYSTA implant (arrow) compared to a quarter

DURYSTA is a very small implant that will slowly release medication directly into the eye to lower eye pressure for glaucoma patients. It is the first and currently the only dissolvable implant for treatment of glaucoma.

Glaucoma is a medical condition where the pressure inside the eye is too high, leading to progressive optic nerve damage. Very commonly, eye drops are used to lower the eye pressure. Typically, eye drops from the prostaglandin class are the first ones chosen by most ophthalmologists to treat glaucoma.

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What is the Hydrus Microstent?

Hydrus Microstent

The Hydrus Microstent is a MIGS device (Minimally Invasive Glaucoma Surgery) used at the time of cataract surgery to lower pressures in patients with glaucoma. It is one of the larger of the MIGS devices that exists on the market today.

Glaucoma is a medical condition where the pressure inside the eye is too high, leading to progressive optic nerve damage. To understand how the Hydrus Microstent works, think of a road with a long drain and sewer system along the entire side of the road. The grating of the drain is called the trabecular meshwork inside the eye, and the sewer system directly underneath the drain is Schlemm’s Canal. In this analogy, glaucoma would be an overflow of the storm water.

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What is the iStent inject?

iStent inject

The iStent inject Trabecular Micro-Bypass System is used at the time of cataract surgery to lower pressures in patients with glaucoma. It is made by Glaukos, the company that also makes the original iStent Micro-Bypass Stent. The main difference between the iStent inject and the original iStent is that with the iStent inject, two stents are utilized, whereas the original iStent only uses one stent. The iStent inject is also significantly smaller, with the largest dimension only measuring 360 μm (or 0.360 mm) long.

Glaucoma is a medical condition where the pressure inside the eye is too high, leading to progressive optic nerve damage. Open angle glaucoma, the most common form of glaucoma, is essentially a backing-up of fluid due to a drain that has become increasingly clogged. The main drain in the eye is called the trabecular meshwork.

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What is the CyPass Micro-Stent?

CyPass Micro-Stent

The CyPass Micro-Stent is a small medical device used at the time of cataract surgery to lower pressures in patients with glaucoma.

Glaucoma is a medical condition where the pressure inside the eye is too high, leading to progressive optic nerve damage. Open angle glaucoma, the most common form of glaucoma, is essentially a backing-up of fluid due to insufficient outflow through the natural drainage system.

In the eye, there are two distinct drainage systems: the traditional trabecular meshwork, and the uveoscleral pathway. Many of the more potent glaucoma eye drops work to decrease eye pressure by increasing the flow through the uveoscleral pathway.

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What is the iStent?

The Glaukos iStent

The iStent Trabecular Micro-Bypass Stent is a tiny medical device used at the time of cataract surgery to lower pressures in patients with glaucoma. It is so small, that at its largest dimension, it is only 1 mm long.

Glaucoma is a medical condition where the pressure inside the eye is too high, leading to progressive optic nerve damage. Open angle glaucoma, the most common form of glaucoma, is essentially a backing-up of fluid due to a drain that has become increasingly clogged. The main drain in the eye is called the trabecular meshwork.

The iStent is placed within the trabecular meshwork, creating an open passage though this clogged drain. The Retention Arches (see above image) keep the iStent buried in position within the trabecular meshwork, and only the Snorkel is exposed. The Lumen of the Snorkel allows the fluid in the eye to easily bypass the trabecular meshwork, and in turn, results in a lower intraocular pressure.

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